EVIDENCE-BASED

Ciprofloxacin

WHO ATCJ01MA02INNCiprofloxacin

Ciprofloxacin is a fluoroquinolone antibiotic used for selected bacterial infections. Because systemic fluoroquinolones can cause serious and sometimes disabling adverse effects, ciprofloxacin should be used only when the expected benefit justifies the risk for the specific infection.

At a glance

Quick facts

Drug snapshot
Drug class
Fluoroquinolone antibiotic
Main use
Selected bacterial infections
Routes
Oral · IV; topical products exist
WHO ATC
J01MA02
Key safety
Serious fluoroquinolone warnings
Stewardship
Use only for appropriate bacterial indications

Names & terminology

How this entity may be named or searched

Canonical generic name
Ciprofloxacin
Salt name
Ciprofloxacin hydrochloride appears in product labeling
Brand example
Cipro
Formulation context
Immediate-release, suspension and extended-release products have different instructions.

Structured drug profile

Drug profile

INN data
INNCiprofloxacinInternational nonproprietary name.
WHO ATCJ01MA02WHO Anatomical Therapeutic Chemical classification.
Drug classFluoroquinolone antibioticPharmacologic / therapeutic class.
MechanismInhibits bacterial DNA gyrase and topoisomerase IV.Mechanism summarized at reference level.
RouteOral · intravenous; topical eye/ear products also existAvailable routes depend on the specific product.
Main usesSelected susceptible bacterial infectionsApproved indications can differ by country and formulation.
Key safety contextTendon injury · peripheral neuropathy · CNS effects · other serious fluoroquinolone warningsCheck the exact product label and patient-specific contraindications.
Monitoring / reviewIndication / culture context · renal function · interacting medicines · adverse effectsClinical monitoring depends on indication, dose and patient factors.

What is ciprofloxacin?

Ciprofloxacin is a fluoroquinolone antibiotic used for selected bacterial infections. It does not treat viral infections such as colds or influenza.

What is ciprofloxacin used for?

Ciprofloxacin treats or prevents selected infections caused by susceptible bacteria. It does not treat viral infections such as colds or influenza, and unnecessary antibiotic use contributes to antimicrobial resistance. [1]

How ciprofloxacin works

Ciprofloxacin inhibits bacterial enzymes needed for DNA replication, which stops susceptible bacteria from multiplying and surviving.

Forms and formulations

Systemic ciprofloxacin includes oral tablets, suspension and intravenous formulations. Eye and ear products also exist, but their dosing is not interchangeable with systemic products.

Country / market layer

Brands & formulations by country

Selected registered products and formulations differ by market. African tabs use national regulatory records or regulator-backed public registration data.

Local availability
🇳🇬
NigeriaExamples in NAFDAC Greenbook
Source ↗
Brand / productFormStrengths / notes
Emzor CiprofloxacinTablet500 mg
Afrab CiprofloxacinCaplet500 mg
PhilocipSolution for injection / infusion200 mg/100 mL
Examples are not a complete product register and do not imply current pharmacy stock. Registration status, strengths and legal availability can change. Antibiotic examples describe registration / product records only; they do not imply clinical appropriateness for a particular infection.

How ciprofloxacin is taken

Oral products include tablets, suspension and extended-release formulations. Instructions differ by formulation and infection. Ciprofloxacin should not be taken together with certain antacids, mineral supplements or products containing calcium, magnesium, aluminum, iron or zinc without spacing the doses as directed, because absorption can be reduced. [1]

Side effects

Common adverse effects can include nausea, diarrhea, headache or dizziness. Serious effects can include tendon inflammation or rupture, peripheral neuropathy, central nervous system effects and severe allergic reactions. Medical advice should be sought promptly for serious or unusual symptoms. [1] [2]

Major fluoroquinolone warnings

Systemic fluoroquinolones, including ciprofloxacin, are associated with serious adverse effects involving tendons, muscles, joints, peripheral nerves and the central nervous system. FDA has advised restricting their use for certain uncomplicated infections when other treatment options are available. [1] [2]

Interactions

Antacids and products containing calcium, magnesium, aluminium, iron or zinc can reduce oral absorption if taken too close to ciprofloxacin. Several medicines can also alter rhythm or other safety risks; check the exact label.

Pregnancy & breastfeeding

Pregnancy and breastfeeding decisions should be individualized because infection severity, alternatives and product labeling matter. A prescriber should review the clinical context.

Overdose and accidental extra doses

Suspected overdose requires urgent poison-centre or medical advice. Management depends on the amount, formulation, symptoms and kidney function.

Antibiotic stewardship

Ciprofloxacin should be used for bacterial infections where it is appropriate, not for viral illnesses. The choice of antibiotic depends on infection site, local resistance patterns, microbiology results, patient factors and safer alternatives. [1]

Common questions

Frequently asked questions

EVIDENCE-BASED

Sources

Clinical statements in this reference are linked to named public-health, regulatory or guideline sources.

  1. 1. MedlinePlus. Ciprofloxacin Drug Information, revised August 2026. Source ↗
  2. 2. FDA. Fluoroquinolone Drug Safety Communication on disabling side effects. Source ↗

This medicine reference is based on trusted medical and regulatory sources and is awaiting clinician review. It is not a substitute for personalized medical advice.