CLINICIAN REVIEWEDEVIDENCE-BASED

Kidney stones

Kidney stones are hard mineral deposits that form in the urinary tract. Small stones may pass with little difficulty, while a stone that enters and blocks a ureter can cause severe colicky pain, blood in the urine, nausea and—in the presence of infection—a urologic emergency.

At a glance

Quick facts

Condition snapshot
Category
Urinary stone disease
Common type
Calcium stone
Classic symptom
Severe flank pain
Blood in urine
Common
Main concern
Obstruction + infection
Treatment
Passage, removal or fragmentation
Medically reviewed

Dr. Francis Chibueze Nwokpoku

Medical Officer · 9th Division Hospital, Nigerian Army

Reviewed for clinical accuracy, important omissions and patient-facing safety wording.

Names & terminology

How this entity may be named or searched

Kidney stone
A solid mineral deposit formed in the kidney or urinary tract.
Nephrolithiasis
Medical term for stones in the kidney.
Urolithiasis
Broader term for stones anywhere in the urinary tract.
Renal colic
Severe, often wave-like pain caused by obstruction as a stone moves through the ureter.

Structured entity profile

Clinical profile

Condition data
NatureMineral crystal formationStones form when urine becomes concentrated with stone-forming substances.
TypesSeveral compositionsCalcium oxalate is most common; uric acid, struvite and cystine stones also occur.
SymptomsOften begin with ureteral obstructionFlank or abdominal pain, hematuria, urinary symptoms, nausea and vomiting are typical.
DiagnosisImaging + urine / blood testsCT, ultrasound or other imaging defines stone size, location and obstruction.
TreatmentSize- and location-dependentSmall stones may pass; larger or complicated stones may need procedures.
PreventionStone-specificHydration, diet and medicine depend on stone type and metabolic risk.

Overview

Kidney stones form when minerals or salts crystallize and aggregate in the urinary tract. Calcium oxalate stones are the most common, but uric acid, struvite and cystine stones have different causes and prevention strategies. [1]

A stone may remain in the kidney without symptoms. Pain typically begins when it moves into the ureter and obstructs urine flow. Obstruction combined with urinary infection can rapidly become dangerous and requires urgent drainage and antibiotic treatment. [1] [2]

Symptoms and warning signs

Typical symptoms include sharp pain in the back, side, lower abdomen or groin; blood in the urine; urinary urgency or pain with urination; nausea and vomiting. Pain may come and go in waves as the ureter contracts around the stone. [2]

SYMPTOM MATRIX

Stone symptoms depend on location, obstruction and infection

Fever or systemic illness with an obstructed urinary tract is an urgent pattern.

Urinary tract
Typical renal colic
  • Sharp flank or side pain
  • Pain radiating toward the groin
  • Blood in the urine
  • Nausea or vomiting
  • Pain that comes in waves
Can also occur
  • Urinary urgency or frequency
  • Pain during urination
  • Cloudy or foul-smelling urine
  • Small-volume urination
  • No symptoms with a non-obstructing stone
Urgent assessment
  • Fever or chills with stone symptoms
  • Inability to urinate
  • Severe persistent pain with vomiting
  • Signs of sepsis or collapse

An infected obstructed urinary tract is a urologic emergency and needs urgent decompression and antibiotics.

Diagnosis

Diagnosis uses symptom history, examination, urine and blood tests plus imaging. Imaging identifies stone size and location and whether urine flow is obstructed. CT is highly sensitive; ultrasound is frequently used when avoiding radiation is important, including many pregnancy pathways. [3]

Urinalysis can show blood, infection or crystals, while blood tests assess kidney function and metabolic contributors. When a stone is passed or removed, analysis of its composition helps guide recurrence prevention. Recurrent stone formers may undergo 24-hour urine and other metabolic testing. [1] [3]

Diagnostic pathway

Locate the stone, assess obstruction and check for infection

Stone size and location matter, but infection and kidney function determine urgency.

Imaging + urine testing
1Assess symptoms and urgencySevere flank pain, fever, solitary kidney or inability to urinate changes the urgency of evaluation.
2Check urine and bloodLook for hematuria, infection, kidney impairment and metabolic clues.
3Image the urinary tractUse CT or ultrasound according to presentation, age, pregnancy status and local practice.
4Plan passage or interventionStone size, location, pain, obstruction and infection guide management.
UrinalysisCommonblood + infection
CT / ultrasoundCore imagingsize + location + obstruction
Stone analysisIf availableprevention strategy

Imaging choice varies with age, pregnancy, recurrence history and clinical urgency; radiation exposure is considered when CT is selected. Source [3]

Stone type changes prevention

Calcium oxalate, uric acid, struvite and cystine stones arise from different risk patterns. Stone analysis and metabolic evaluation are especially useful in recurrent disease because prevention should address the specific urinary chemistry rather than rely on a universal diet. [1]

Treatment and management

Small uncomplicated stones may pass spontaneously with pain control, hydration appropriate to the clinical situation and follow-up. Treatment is escalated when pain is uncontrolled, the stone is unlikely to pass, obstruction threatens kidney function or infection is present. [1]

1 expert note

Small stones can often pass without a procedure. Pain control, the ability to maintain hydration, obstruction, infection and the course of symptoms help determine whether outpatient care remains appropriate or escalation is needed.

Procedures include ureteroscopy, shock-wave lithotripsy and percutaneous stone removal, selected according to stone size and location. Prevention after an episode may include higher fluid intake, dietary changes and medicine targeted to the stone type or 24-hour urine findings. [1]

Treatment & care hub

Relieve obstruction, control pain and prevent recurrence

Treatment is based on stone size, location, infection, kidney function and likelihood of spontaneous passage.

Stone management
Conservative passageSelected small stones

Allow spontaneous passage when safe

Pain control and follow-up are used when the stone is likely to pass and there is no dangerous obstruction or infection.

Urgent drainageInfected obstruction

Decompress the urinary tract

Obstruction with infection requires urgent drainage and antibiotics rather than waiting for passage.

Stone procedureWhen needed

Remove or fragment the stone

Ureteroscopy, shock-wave lithotripsy or percutaneous approaches are selected according to anatomy and stone burden.

PreventionAfter recovery

Reduce recurrence risk

Hydration, diet and medicines are tailored to stone composition and metabolic findings.

Preventing future stones

NIDDK advises adequate fluid intake for most stone formers unless a clinician has given a different fluid plan. Sodium, animal protein, calcium and oxalate advice should be individualized because inappropriate restriction—especially of normal dietary calcium—can be counterproductive for some calcium oxalate stone formers. [1]

1 expert note

In follow-up I emphasize adequate fluid intake because concentrated urine promotes stone formation. The exact fluid target should be individualized to the person and clinical circumstances.

United States lifetime estimate

Kidney stones affect a substantial minority of adults

NIDDK estimates about 11% of men and 6% of women in the United States have a kidney stone at least once during their lifetime.

NIDDK Kidney Stones — Definition & Facts ↗
Men with kidney stone historyAbout 11%lifetime estimate
WomenAbout 6%
RecurrenceCommon
PreventionStone-specific
Source: NIDDK Kidney Stones — Definition & Facts. These are U.S. lifetime estimates from cited epidemiologic data.

Common questions

Frequently asked questions

Reference content

Sources

  1. NIDDK, NIH — Kidney Stones — Definition & Facts
  2. NIDDK, NIH — Kidney Stones — Symptoms & Causes
  3. NIDDK, NIH — Diagnosis of Kidney Stones

This article is based on trusted medical sources and has undergone clinician review. It is not a substitute for personalized medical advice.